| MAGIC BULLET (CONTINUED) email:curepeyronies@yahoo.com |
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- The researchers noted that in their opinion this was the first report
showing that pharmacolgical intervention was potentially useful in the
treatment of PD when given at the early, unstable and progressive
stage of the disease.
- Further studies are needed to address whether this intervention
induces regression of fibrotic plaque and correction of penile curvature
if administered at the chronic or stable phase of the disease.
- What follows are charts based on the findings from the research paper.
Note that I couldn't reproduce some of the data in the charts with the
absolute exact values as the researchers, but my values below are very
close. For example, I couldn't tell if penile curvature in the control group
was 5,6, or 7 degrees. Also, for simplicity sake, I left out some data that
were in the original research and printed in the journal article.
In this finding, IN-1130 essentially
corrects penile curvature of rats who
are in the early stages of Peyronies
Disease. Each bar depicts mean
values for 6 animals per group. It is
interesting to note that those rats with
Peyronies who were treated with
Saline solution developed an even
more severe penile curvature.
IN-1130 reduces transforming growth
factor expression. Each bar represents
the mean values of 6 animals per
group. The values are presented as a
percentage of the total number of cells
counted. As noted earlier, over
expression of TGF is thought to result
in Peyronies symptoms and a
decrease in the activity ameliorates the
symptoms.