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   NEWS IN BRIEF Page 3

My Complaint About The AMA

The Journal of the American Medical Association,
October 14, 2009, published a widely circulated and quoted
article about the comparative effectiveness of minimally
invasive RPs vs open radical prostatectomies. One of their
most important findings was that those men who underwent a
minimally invasive procedure developed a greater percentage
of ED as compared to the open group, although both
surgeries raised the risk of developing ED. What they omitted
is that very often this ED manifests itself as PD or PD like
symptoms. This is a major over site as one study shows that
almost 20% of all men who underwent a RP developed PD. By
its very nature PD is an ED condition.  How can they leave out
such a significant finding?

Another Possible Promising Treatment For Early PD

This is a very important article for men with early PD

Johns Hopkins is conducting research on how to protect
nerve tissue following a RP.  In one experiment, they
deliberately damaged the nerves of laboratory rats that
controlled sexual function.  Subsequently, they used
Losartan, a fairly common drug used to treat hypertension,
because it has demonstated the ability to maintain the health
of blood vessels. In laboratory studies it was shown to
enhance erection recovery and limit penile deformity and
scarring in rats.
Scarring and penile deformity- can someone
say PD.  If I were a man with early PD, this is another avenue
I would pursue. This drug is relatively inexpensive with very
few serious side effects. When will they conduct an
experiment to find out if this drug can prevent or reverse PD
symptoms?

Response to one reader

I strongly encourage reader feedback even if it is negative.

One reader sent me an email commenting that I do not update
my website very often, my news becomes "stale" and he can
view the same news on other blogs and forums. I would like
to respond.

Other blogs and forums are very valuable and serve an
important role in the dissemination of PD news.  When I
started this site, I hoped to perform an additional service to
the PD community, not better, but somewhat different. The
articles you usually see posted on other blogs, sites and
forums are generally short abstracts of much longer articles.  
It takes me some time to locate, obtain, purchase, read and
review the full text of these articles.  For example, my article
in this edition on a promising surgical technique is 5 pages,
the abstract which is readily available through Google is just
a few paragraphs. Secondly, in my opinion, I provide a
valuable service to readers by analyzing these articles and
providing my opinions and suggestions.

Hopefully, despite the criticisms, this reader will still keep
visiting my website.

Summary

Unfortunately,  much of the literature on PD consists of
summaries on the current state of medical management.  In
the Journal of Andrology, July/August 2009, there was a
particularly good discussion of current medical findings. Here
is a summary of this article.

  • spontaneous resolution is a rare occurrence and 30-40%
    of men experience a progression of their condition
  • in an American study almost 9% of men who presented
    for prostate cancer screening had PD
  • in the past 250 years there has been “meager”
    advancement in the understanding of PD etiology and
    effective management
  • despite the lack of definitive evidence for Vitamin E as an
    effective treatment, urologists commonly prescribe this
    as a first line treatment
  • currently, oral treatment has shown negligible success in
    treating PD . (This was before the Iranian paper on
    pentoxifylline)