The Journal of the American Medical Association, October 14, 2009, published a widely circulated and quoted article about the comparative effectiveness of minimally invasive RPs vs open radical prostatectomies. One of their most important findings was that those men who underwent a minimally invasive procedure developed a greater percentage of ED as compared to the open group, although both surgeries raised the risk of developing ED. What they omitted is that very often this ED manifests itself as PD or PD like symptoms. This is a major over site as one study shows that almost 20% of all men who underwent a RP developed PD. By its very nature PD is an ED condition. How can they leave out such a significant finding?
Another Possible Promising Treatment For Early PD
This is a very important article for men with early PD
Johns Hopkins is conducting research on how to protect nerve tissue following a RP. In one experiment, they deliberately damaged the nerves of laboratory rats that controlled sexual function. Subsequently, they used Losartan, a fairly common drug used to treat hypertension, because it has demonstated the ability to maintain the health of blood vessels. In laboratory studies it was shown to enhance erection recovery and limit penile deformity and scarring in rats. Scarring and penile deformity- can someone say PD. If I were a man with early PD, this is another avenue I would pursue. This drug is relatively inexpensive with very few serious side effects. When will they conduct an experiment to find out if this drug can prevent or reverse PD symptoms?
Response to one reader
I strongly encourage reader feedback even if it is negative.
One reader sent me an email commenting that I do not update my website very often, my news becomes "stale" and he can view the same news on other blogs and forums. I would like to respond.
Other blogs and forums are very valuable and serve an important role in the dissemination of PD news. When I started this site, I hoped to perform an additional service to the PD community, not better, but somewhat different. The articles you usually see posted on other blogs, sites and forums are generally short abstracts of much longer articles. It takes me some time to locate, obtain, purchase, read and review the full text of these articles. For example, my article in this edition on a promising surgical technique is 5 pages, the abstract which is readily available through Google is just a few paragraphs. Secondly, in my opinion, I provide a valuable service to readers by analyzing these articles and providing my opinions and suggestions.
Hopefully, despite the criticisms, this reader will still keep visiting my website.
Summary
Unfortunately, much of the literature on PD consists of summaries on the current state of medical management. In the Journal of Andrology, July/August 2009, there was a particularly good discussion of current medical findings. Here is a summary of this article.
spontaneous resolution is a rare occurrence and 30-40% of men experience a progression of their condition
in an American study almost 9% of men who presented for prostate cancer screening had PD
in the past 250 years there has been “meager” advancement in the understanding of PD etiology and effective management
despite the lack of definitive evidence for Vitamin E as an effective treatment, urologists commonly prescribe this as a first line treatment
currently, oral treatment has shown negligible success in treating PD . (This was before the Iranian paper on pentoxifylline)